Akihito Kuboki

Research Associate


Research Associate, Monell Chemical Senses Center


Ph.D., Neuroscience, The Jikei University School of Medicine (Tokyo, Japan)
M.D., St. Marianna University School of Medicine (Kanagawa, Japan)

Laboratory Of

Dr. Johannes Reisert

Research Summary

My research involves understanding the mechanisms of adaptation in olfactory sensory neurons to an odorous stimulus and the factors involved in homeostatic regeneration of the olfactory epithelium. I will be studying the first step of olfactory perception in order to investigate the pathophysiology of olfactory dysfunction in the periphery. I am using electrophysiological as well as cell biological approaches to address these questions. Over the course working as a physician-scientist with a specialization in otorhinolaryngology, I am also interested in ENT-related medical research.


olfaction, electro-olfactogram, electrophysiology, signal transduction, olfactory dysfunction

Representative Publications

Kikuta S, Kuboki A, Yamasoba T. (2021) Protective effect of insulin in mouse nasal mucus against olfactory epithelium injury. Front Neural Circuits. 15:803769. doi: 10.3389/fncir.2021.803769.

Kuboki A, Kikuta S, Otori N, Kojima H, Matsumoto I, Reisert J, and Yamasoba T. (2021) Insulin-dependent maturation of newly generated olfactory sensory neurons after injury. eNeuro. 19;8(3):ENEURO.0168-21.2021. doi: 10.1523/ENEURO.0168-21.2021.

Kuboki A, Kanaya H, Nakayama T, Konno W, Goto K, Nakajima I, Kashiwagi T, Hirabayashi H, Haruna SI. (2019) Prognostic value of C-reactive protein/albumin ratio for patients with hypopharyngeal and laryngeal cancer undergoing invasive surgery involving laryngectomy. Head Neck. 41(5): 1342-1350.

Kuboki A, Kikuchi S, Asaka D, Onda N, Nakayama T, Kojima H, Otori N. (2018) Nasal silicone splints and quilting sutures using a septum stitch device following septoplasty: a prospective comparative study. Eur Arch Otorhinolaryngol. 275(7): 1803-1809.

Kikuta S, Matsumoto Y, Kuboki A, Nakayama T, Asaka D, et al. (2016) Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder. Sci Rep. 6, 35361.

Akihito Kuboki

Contact Information

(267) 519-4793