Affiliations
Postdoctoral Fellow, Monell Chemical Senses Center
Education
Ph.D., Microbiology, Fudan University (Shanghai, China)
Laboratory Of
Dr. Peihua Jiang
Research Summary
Tuft cells are chemosensory cells in the intestinal epithelium which express a number of taste-signaling elements. Despite being discovered decades ago, the function of tuft cells in the small intestine was only recently discovered. Tuft cells mediate host defense against parasitic infection or other pathogens by regulating type 2 immunity. My research interest is clarifying the parasites’ ligands and sensing receptors in tuft cells.
Keywords
tuft cells, type 2 immunity, parasitic infections
Representative Publications
Srinivasalu N*, Lu C*, Pan M, Reinach PS, Wen Y, Hu Y, Qu J, Zhou X. (2018) Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. Invest Ophthalmol Vis Sci. 59, 4318-4325. (*equal contribution)