Kuei-Pin Huang

Research Associate

Affiliations

Research Associate, Monell Chemical Senses Center

Education

Ph.D, Physiology, University of California, Davis

Laboratory Of

Dr. Amber Alhadeff

Research Summary

Food consumption induces the release of gut signals that are locally sensed by the gastrointestinal tract-innervated peripheral nerves. These signals are rapidly conducted to the different brain regions, which modulate the eating behaviors.

My research interest is in understanding how different nutrients (sugars, fat, and proteins) are sensed by the peripheral nervous system and how these different signals modulate food intake in physiological and disease stages. We use different mouse models and the latest neuroscience tools to record in vivo neuronal activity and manipulate the specific population of neurons to reveal the potential target for eating disorders.

Keywords

gut-brain axis, vagal afferent neurons, gut hormones, food intake, physiology, obesity

Representative Publications

Huang, K. P., Goodson, M. L., Vang, W., Li, H., Page, A. J., Raybould, H. E. (2020). Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet. International Journal of Obesity, 1-10.

Huang, K. P., Raybould, H. E. (2020). Estrogen and Gut Satiety Hormones in Vagus-Hindbrain Axis. Peptides, 170389.

Huang, K. P., Ronveaux, C. C., Knotts, T. A., Rutkowsky, J. R., Ramsey, J. J., Raybould, H. E. (2020). Sex differences in response to short-term high fat diet in mice. Physiology & Behavior, 112894.

Huang, K. P., Ronveaux, C. C., de Lartigue, G., Geary, N., Asarian, L., Raybould, H. E. (2019). Deletion of leptin receptors in vagal afferent neurons disrupts estrogen signaling, body weight, food intake and hormonal controls of feeding in female mice. American Journal of Physiology-Endocrinology and Metabolism, 316(4), E568-E577.

Contact Information

kphuang@monell.org