Affiliations
Senior Research Associate, Monell Chemical Senses Center
Education
PhD, Analytical Chemistry; University of Florida
Laboratory Of
Dr. Bruce Kimball
The George Preti Research Support Core for Analytical Chemistry
Research Summary
Mass spectrometry is arguably the most important analytical technique considering its selectivity, sensitivity, and informing power, among other qualities. I have sought to apply mass spectrometry’s capabilities throughout my various research endeavors that span across the discipline of analytical chemistry, such as analyzing pigments and dyes in works of art and deciphering metabolic and lipidomic changes as a function health status in an assortment of human and animal matrices. With my post-doctoral experience at the Hollings Marine Laboratory, I honed my interests of lipids with untargeted, global analyses to decipher the lipidome of diverse biological samples (plasma, muscle, liver, brain) for aquatic specimens (saltwater fish, sea turtles) and marine mammals (bottlenose dolphins, Florida manatees). With the Preti Core, I am now providing lipidomic, metabolomic, and targeted quantitation for the myriad projects from Monell researchers, collaborators, and external clients.
Keywords
lipidomics, metabolomics, quantitation, analytical chemistry, liquid chromatography tandem mass spectrometry (LC/MS/MS)
Representative Publications
Peyrot des Gachons, C.; Willis, C.; Napolitano, M. P.; O’Keefe, A. J.; Kimball, B. A.; Slade, L.; Beauchamp, G. K. “Oleocanthal and oleacein from privet leaves: an alternative source for high-value extra virgin olive oil bioactives” Int. J. Mol. Sci. 2024, 25, 12020.
Griffin, E. K.; Costa, K. A.; Aristizabal-Henao, J. J.; Napolitano, M. P.; Hunter, M. E.; Ferrante, J. A.; Bowden, J. A. “Lipidomics reveals specific lipid molecules associated with cold stress syndrome in the Florida manatee (Trichechus manatus latirostris)” Marine Biology 2021, 168, 81.
Watson, A. M.*; Napolitano, M. P.*; Shock, T. B.; Bowden, J. A.; Frost, J.; Yost, J.; Denson, M. R. “Evaluation of Graded Levels of Soy Oil as a Fish Oil Replacement in High Soy Protein Feeds for Juvenile Red Drum, Sciaenops ocellatus” Aquaculture 2020, 529, 735627. *shared first author
Koelmel, J. P.*; Napolitano, M. P.*; Ulmer, C. Z.*; Vasiliou, V.; Garrett, T. J.; Yost, R. A.; Prasad, M. N. V.; Godri Pollitt, K. J.; Bowden, J. A. “Environmental Lipidomics: Understanding the Response of Organisms and Ecosystems to a Changing World” Metabolomics, 2020, 16, 56. *shared first author
Napolitano, M. P.; Kuo, P. C.; Johnson, J. V.; Arslanoglu, J.; Yost, R. A. “Tandem Mass Spectrometry of Laser-Reduced Anthraquinones for Painted Works and Dyed Cultural Artifacts” Int. J. Mass Spectrom., 2017, 421, 14–24.
