Affiliations
Research Associate, Monell Chemical Senses Center
Education
Ph.D., Plant Science, China Agricultural University (Beijing, China)
Laboratory Of
Dr. Yali Zhang
Research Summary
Taste is a fundamental sense required to perceive food flavor including food taste, texture, temperature, etc. To unravel how animals detect the physical and chemical information from the food environment, we use model organisms such as the fruit fly and mouse to explore the peripheral and central gustatory mechanisms that regulate food preference and feeding behavior.
Keywords
taste, molecular biology, patch-clamp recording, neuroscience, ion channel
Representative Publications
Ting-Wei Mi, John O Mack, Wyatt Koolmees, Quinn Lyon, Luke Yochimowitz, Zhao-Qian Teng, Pei-Hua Jiang, Craig Montell, Yali V. Zhang (2023). Alkaline taste sensation through the alkaliphile chloride channel in Drosophila. Nature Metabolism, 5(3), 466–480.
Zhifang Wang, Tingwei Mi, Yongqiang Gao, Hanqian Feng, Weihua Wu, and Yi Wang. (2022) STOP1 Regulates LKS1 Transcription and Coordinates K+/NH4+ Balance in Arabidopsis Response to Low-K+ Stress. International Journal of Molecular Sciences 23(1), 383.
Tingwei Mi, John O. Mack, Christopher M. Lee, Yali V. Zhang. (2021) Molecular and cellular basis of acid taste sensation in Drosophila. Nature Communications, 12(1), 3730.
Gang-Bin Tang, Ting-Wei Mi, Man-Lian Sun, Ya-Jie Xua, Shu-Guang Yang, Hong-Zhen Du, Saijilafuc, Zhao-Qian Teng, Jun Gao, Chang-Mei Liu. (2020) Overexpression of serotonin receptor 5b expression rescues neuronal and behavioral deficits in a mouse model of Kabuki syndrome. IBRO Reports, 9, 138-146.
Ting-Wei Mi, Xiao-Wen Sun, Zhi-Meng Wang, Ying-Ying Wang, Xuan-Cheng He, Cong Liu, Shuang-Feng Zhang, Hong-Zhen Du, Chang-Mei Liu, Zhao-Qian Teng. (2020) Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2. Experimental Neurobiology, 29, 138-149.
HaiLiang Yan, XiaoWen Sun, ZhiMeng Wang, PeiPei Liu, Ting-Wei Mi, Cong Liu, YingYing Wang, XuanCheng He, HongZhen Du, ChangMei Liu, ZhaoQian Teng. (2019) MiR-137 deficiency causes anxiety-like behaviors in mice. Frontiers in Molecular Neuroscience, 12, 260.
Wenliang Zhu, Boya Zhang, Mengqi Li, Fan Mo, Ting-Wei Mi, Yihui Wu, Zhaoqian Teng, Qi Zhou, Wei Li, Baoyang Hu. (2019) Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. Nature Communications, 10, 928.
Boya Zhang, Yangzhige He, Yanpeng Xu, Fan Mo, Ting-Wei Mi, Qing Sunny Shen, Chunfeng Li, Yali Li, Jing Liu, Yihui Wu, Guilai Chen, Wenliang Zhu, Chengfeng Qin, Baoyang Hu, Guomin Zhou. (2018) Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids. Cell Death & Disease, 9, 719.
Wu, Menghua, Da Zhang, Chunying Bi, Ting-Wei Mi, Wenliang Zhu, Longkuo Xia, Zhaoqian Teng, Baoyang Hu, Yihui Wu. (2018) A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs. Stem Cell Reports, 11, 635-650.
Ying Cheng, Zhi-Meng Wang, Weiqi Tan, Xiaona Wang, Yujing Li, Bing Bai, Yuxin Li, Shuang-Feng Zhang, Hai-Liang Yan, Zuo-Lun Chen, Chang-Mei Liu, Ting-Wei Mi, Shuting Xia, Zikai Zhou, An Liu, Gang-Bin Tang, Cong Liu, Zhi-Jie Dai, Ying-Ying Wang, Hong Wang, Xusheng Wang, Yunhee Kang, Li Lin, Zhenping Chen, Nina Xie, Qinmiao Sun, Wei Xie, Junmin Peng, Dahua Chen, Zhao-Qian Teng, Peng Jin. (2018) Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a. Nature Neuroscience, 21, 1689–1703.
