A pioneer in the use of molecular biology to study cellular mechanisms of taste, Dr. Margolskee was selected by Monell’s Board in August 2014 to become the Center’s third Director. Dr. Margolskee joined Monell’s faculty in 2009 and was appointed Associate Director in 2010.
Dr. Margolskee’s seminal discovery of gustducin, a signaling protein expressed selectively in taste cells, provided the critical knowledge needed to explain how taste receptors detect sweet, bitter and savory tasting molecules. More recently, his research has focused on the mechanisms and functions of taste receptors located in the gastrointestinal tract, gingiva, and in other organs throughout the body.
Dr. Margolskee received his undergraduate degree from Harvard University and his MD-PhD in Molecular Genetics from Johns Hopkins University. He is an author on over 130 peer-reviewed articles, which have been published in such prestigious journals as Nature, Science, Proceedings of the National Academy of Sciences, and Scientific American.